ICMR scientists identify new biomarker for malaria

  1. A team of researchers from Indian Council of Medical Research(ICMR) has identified a new biomarker in the body called as glutamate dehydrogenase of malaria parasite.
  2. This promises to help develop a more sensitive diagnostic test for the malaria disease.
  3. Currently,tests used for diagnosing malaria are based on a gene,Histidine-rich Protein 2(HRP2) replete with amino acid Histidine.However,studies have shown that this gene is often absent in some strains of the malaria parasite.
  4. Consequently,significant levels of malaria infection were going undetected. Scientists across the world have been searching for new biomarkers that would be more effective.
  5. A biomarker or biological marker is a measurable indicator of some biological state or condition.Biomarkers are often measured and evaluated to examine normal biological processes,pathogenic processes or pharmacologic responses to a therapeutic intervention.Biomarkers are used in many scientific fields.
  6. Malaria is a disease caused by Plasmodium parasites that are transmitted to people through the bite of infected female Anopheles mosquitoes.
  7. According to the World Malaria Report 2018, more than 200 million people were affected by malaria in 2017. India (4%) along with Nigeria Democratic Republic of the Congo, Mozambique, and Uganda accounted for nearly 50% of all malaria cases worldwide.


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