Quick, cheap diagnostic test for Haemophilia A

6 min read
  1. The Indian Council of Medical Research (ICMR)’s National Institute of Immunohematology, Mumbai, has developed a cost-effective Point-of-Care (POC) rapid diagnostic test for severe Haemophilia A and Von Willebrand Disease (VWD). This is the first in the world POC test for specific diagnosis of any common bleeding disorder.
  2. The POC test is cost and time efficient. Working cost of these kits is less than ₹50 whereas existing conventional test for the diseases that costs around ₹4,000 to ₹10,000,
  3. Von Willebrand disease (VWD) and haemophilia A are both bleeding disorders that prevent the blood from clotting. Haemophilia A, also called factor VIII (FVIII) deficiency or classic haemophilia, is a genetic disorder caused by missing or defective factor VIII, a clotting protein
  4. Von Willebrand disease (VWD) is a genetic disorder caused by missing or defective von Willebrand factor (VWF), a clotting protein. VWF binds factor VIII, a key clotting protein, and platelets in blood vessel walls, which help form a platelet plug during the clotting process.
  5. Haemophilia A or VWD can cause life-threatening spontaneous or post-traumatic bleeding like brain haemorrhage and gastrointestinal bleed bleeding into joints or superficial bleeding from the nose or gums.

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